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Company: University of Miami
Location: Miami, FL
Employment Type: Full Time
Date Posted: 08/17/2022
Expire Date: 10/17/2022
Job Categories: Healthcare, Other
The Laboratories of Anna Lasorella and Antonio Lavarone in the Sylvester Comprehensive Cancer Center at the University of Miami are seeking two postdoctoral scientists/postdoctoral associates to join our research program in Neuro-Oncology. Our studies focus on the molecular genetics and biology of brain tumors with an emphasis on the characterization and therapeutic targeting of driver mutations involved in the pathogenesis and progression of malignant brain tumors. We use a diverse combination of experimental approaches, including next-generation DNA/RNA sequencing, single cell RNA and ATAC sequencing and special transcriptomic. We model malignant glioma using glioma patient derived organoids and xenografts, and engineered mouse brain tumor models to understand tumor biology and design rational therapeutic strategies for patients with brain tumors. The labs are also a dynamic environment in which bench work and computational/systems biology intersect to facil itate biological research and identify new avenues through which to understand the complexity of brain cancer.
The ideal candidate will have research experience in cellular and molecular biology and mouse models of disease. Candidates should have a proven track record of peer-reviewed publications in respected journals. Previous experience in cancer biology, pharmacology, bioinformatics, and cancer genomics would be a positive consideration. We also encourage candidates who are trained in other research fields, such as developmental biology, immunology, and neuroscience, to apply these positions if they feel their skill sets are translatable to the goals described above. Strong mentoring support is available from Dr. Lasorella and Dr. Iavarone to write and win competitive postdoctoral grants.
Investigates the feasibility of applying a wide variety of scientific principles and theories.
Maintains substantial knowledge of state-of-the-art principles and theories.
Develops advanced analytical models and systems and provides solutions and analyses to support strategic and tactical decisions.
Independently perform bench work involving DNA/RNA sequencing, single cell RNA and ATAC sequencing and special transcriptomic and mammalian cell culture/cell-based assays of tumor cell growth and response to therapeutic agents.
Conduct mouse surgeries and subsequent animal health monitoring for intracranial tumors models.
Evaluate and interpret collected data and prepare reports and analyses setting forth progress, adverse trends, and appropriate recommendations or conclusions.
Review scientific literature to follow new developments and to obtain information regarding previous experiments to aid in the design and development of original procedures and techniques.
Independently write and submit (with appropriate mentorship) postdoctoral fellowship grants.
Communicate scientific results to colleagues, mentors, and the broader scientific community.
This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities, as necessary.
MD or Ph.D. in relevant field
No prior experience required, life science research experience preferred
Technical aptitude for learning and executing complex experimental techniques for molecular biology, cell-based assays, single cell assays, and rodent procedures.
Impeccable experimental documentation and organized record-keeping skills.
Ability to effectively work independently and in a team environment in a fast-paced lab.
Skill in collecting, organizing, and analyzing data.
Ability to recognize, analyze, and solve a variety of problems.
Ability to exercise sound judgment in making critical decisions.